Schizophrenia polygenic risk predicts general cognitive deficit but not cognitive decline in healthy older adults
نویسندگان
چکیده
منابع مشابه
Predicting cognitive decline in healthy older adults.
OBJECTIVE Authors performed a neuropsychological determination of which individuals in a group of community-dwelling, healthy elderly volunteers would develop cognitive decline. METHODS A group of 155 volunteers reporting good memory and thinking participated in a prospective study over 4 years. Authors monitored cognitive functioning and incidence of Mild Cognitive Impairment (MCI)/Alzheimer...
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Neurocognitive dysfunction is common in schizophrenia but its course and determinants remain uncertain. Our aim was to analyse if premorbid school performance and the severity of illness and functioning predict change in cognition in schizophrenia in a general population sample. The sample included cases with schizophrenia spectrum disorder from the Northern Finland Birth Cohort 1966. Data on s...
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OBJECTIVE The ability to recognize familiar people is impaired in both Mild Cognitive Impairment (MCI) and Alzheimer's Dementia (AD). In addition, both groups often demonstrate a time-limited temporal gradient (TG) in which well known people from decades earlier are better recalled than those learned recently. In this study, we examined the TG in cognitively intact elders for remote famous name...
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ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2020
ISSN: 2158-3188
DOI: 10.1038/s41398-020-01114-8